Positioned at a prominent location along Michigan Avenue, the project and its surrounding site will serve as a new campus gateway for the University, with a landscaped courtyard, a new Trinity Fountain, and realigned pathways, with intentional sightlines to build connections across campus. The exterior of the building is designed to match the aged facades of surrounding campus buildings, with century-old stone that has been salvaged from the 1926 Church of the Transfiguration in Philadelphia.

The new nursing building will conform to the massing and siting principles outlined in the 2012 Campus Master Plan and the 2019 Feasibility Study, both completed by Ayers Saint Gross. Sustainability goals are set high, targeting LEED Gold and seeking a WELL Building Standard Certification. The project is being completed in association with Robert A.M. Stern Architects and Michael Vergason Landscape Architects.

Inside, the building includes modern, immersive learning spaces, simulation labs, science labs, virtual reality, student spaces, and public and office space.